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34 Mice with Woolly Mammoth Genes: A Step Closer to De-Extinction

Scientists at Colossal Biosciences have created 34 mice with genetic modifications that mimic traits of woolly mammoths. These “woolly mice” are a significant milestone in the company’s mission to resurrect the extinct woolly mammoth. The team identified 10 genes linked to mammoth-like features, such as long, wavy, and light-colored fur, and used CRISPR and other gene-editing techniques to alter these genes in mouse embryos. All 34 pups born from these experiments appear healthy. The project aims to eventually edit the genomes of Asian elephants, which are genetically related to mammoths, to create a mammoth-like elephant capable of surviving in Arctic conditions. However, experts caution that the ecological impact of such reintroductions is uncertain. The company also plans to de-extinct other species like the dodo and thylacine, and is exploring ways to enhance genetic diversity in endangered species like the pink pigeon and Hawaiian honeycreeper.

Source: www.technologyreview.com

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