In a 2,000-acre preserve in the northern US, three snow-white wolves roam. Colossal Biosciences claims these animals are dire wolves, a species extinct for 13,000 years, brought back through biotechnology. The company used DNA from dire wolf bones and gene editing to introduce 20 genetic changes across 14 genes into gray wolf cells. These modifications aimed to increase size, alter facial features, and achieve a snow-white appearance. The wolves, named Romulus, Remus, and Khaleesi, were born through cloning. However, some scientists argue that these animals are not true dire wolves but modified gray wolves, as dire and gray wolves diverged evolutionarily about 4 million years ago. Colossal also cloned several red wolves, the most endangered wolf species in the world. The project’s broader goal is to develop biotechnology tools for conservation, though it has sparked debate over the definition of species revival.
Science girl
@gunsnrosesgirl3
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18h You’re hearing the first howl of a dire wolf in over 10,000 years
Back from extinction
using ancient DNA from fossils up to 72,000 years old, Colossal reconstructed a full genome , through precise CRISPR edits, and brought this species to life
Spencer
@416Spencer
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14h GROK: Colossal didn’t use actual dire wolf DNA directly in these wolves. Instead, they analyzed ancient DNA from a 13,000-year-old tooth and a 72,000-year-old ear bone to identify key genetic differences. Using CRISPR, they edited 14 genes in gray wolf cells to express 20 dire
Facts & Wisdom
@FactPoint
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33m Colossal Biosciences has achieved a groundbreaking feat by bringing the extinct dire wolf back to life after more than 10,000 years. Utilizing advanced genetic engineering, scientists reconstructed the dire wolf’s genome from ancient DNA and edited the genes of modern gray
The Statesman
@TheStatesmanLtd
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1h Colossal claims that three genetically modified grey wolf pups – two males called Remus and Romulus born in October, and a female called Khaleesi born in January – are in fact dire wolves.
#colossal #colossalbioscience #Wolves #Science #TheStatesman
TRT World
@trtworld
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16h Geneticists at Colossal Biosciences have brought back dire wolves — the Ice Age predators extinct for 13,000 years — stunning the scientific world and rewriting the rules of genetics
https://trt.global/world/article/0e459f51c142…
Rocco Strydom
@sgmpodcst
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6h A Scientist Just Brought Back the Dire Wolf Using AI and CRISPR
Benn Lamm’s biotech startup
@colossal
used gene-editing and ancient DNA to revive a predator that vanished over 10,000 years ago. Now, three pups are alive and howling.
In a milestone for science, technology, and
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